Portfolio Press Release
Trius Therapeutics ICAAC 2010 Poster Sessions
Boston, September 12-15th
Trius Therapeutics, Inc.
September 2010
| Session | Title | Time/Location |
| Pharmacology of Oxazolidinones and Miscellaneous Antibacterial Agents | Absolute Bioavailability of TR-701 FA and Pharmacokinetics after Single and Multiple Intravenous Administration in Healthy Adult Subjects • P. BIEN, P. PROKOCIMER, K. A. MUNOZ, C. BETHUNE | Sunday, September 12, 11:30 AM - 1:30 PM Poster Number A1-013 |
| Pharmacology of Oxazolidinones and Miscellaneous Antibacterial Agents | Population Pharmacokinetic Modeling of TR-700 in Patients with Complicated Skin and Skin Structure Infections. • J. MONDICK, P. BIEN, C. DE ANDA, M. GASTONGUAY, P. PROKOCIMER | Sunday, September 12, 11:30 AM - 1:30 PM Poster Number A1-014 |
| Antibiotic Therapy of Serious Bacterial Infections in Animal Models | Anti-Virulence Effect of TR-700 on MRSA Strains Causing Complicated Skin and Skin Structure Infections (cSSTIs) • J. M. YAMAKI, T. SYNOLD, A. WONG-BERINGER | Monday, September 13, 11:15 AM - 1:15 PM Poster Number B-709 |
| Inhibitors of Metabolic Processes | Structure-based Design of Novel 7-substituted Diaminoquinazoline Antibacterial Agents Targeting Dihydrofolate Reductase (DHFR) • M. HILGERS, T. LAM, J. ZHANG, X. LI, Z. CHEN, M. TRZOSS, C. CREIGHTON, L. KOHEN, M. CUNNINGHAM, B. KWAN, K. NELSON, M. STIDHAM, V. BROWN-DRIVER, K. SHAW, J. FINN | Monday, September 13, 11:15 AM - 1:15 PM Poster Number F1-834 |
| Inhibitors of Metabolic Processes | Structure-Based Design of New DHFR Antibacterial Agents (Part 1): 7-Aryl-2,4-Diaminoquinazolines SAR • X. LI, M. HILGERS, J. ZHANG, Z. CHEN, T. LAM, M. TRZOSS, L. KOHEN, C. CREIGHTON, M. CUNNINGHAM,K. NELSON, B. KWAN, M. STIDHAM, V. BROWN- DRIVER, K. SHAW, J. FINN | Monday, September 13, 11:15 AM - 1:15 PM Poster Number F1-835 |
| Inhibitors of Metabolic Processes | Structure-Based Design of New DHFR Antibacterial Agents (Part 2): 7-Benzimidazol-1-yl-2,4-Diaminoquinazolines SAR • J. FINN, T. LAM, J. ZHANG, M. HILGERS, X. LI, M. TRZOSS, L. KOHEN, M. CUNNINGHAM, K. NELSON, M. STIDHAM, V. BROWN-DRIVER, K. SHAW | Monday, September 13, 11:15 AM - 1:15 PM Poster Number F1-836 |
| Inhibitors of Metabolic Processes | Microbiological Profile of Novel 2,4-diaminoquinazoline DHFR Inhibitors • V. BROWN-DRIVER, T. LAM, K. NELSON, A. CASTELLANO, C. CREIGHTON, J. ZHANG, X. LI, Z. CHEN, M. TRZOSS, K. GC, E. BILLER, M. CUNNINGHAM, M. STIDHAM, K. J. SHAW, J. FINN | Monday, September 13, 11:15 AM - 1:15 PM Poster Number F1-837 |
| Inhibitors of Metabolic Processes | Advanced Microbiology and In Vivo Efficacy of Rx101005, a Novel 2,4-Diaminoquinazoline DHFR Inhibitor • V. BROWN-DRIVER, T. LAM, A. CASTELLANO, K. NELSON, K. J. SHAW, J. FINN | Monday, September 13, 11:15 AM - 1:15 PM Poster Number F1-838 |
| New Antifungal Agents | Evaluation of Novel 2,4-Diaminoquinazoline Inhibitors of Candida albicans DHFR • M. HILGERS, M. CUNNINGHAM, B. KWAN, K. NELSON, T. LAM, J. ZHANG, X. LI, Z. CHEN, M. TRZOSS, C. CHREIGHTON, L. KOHEN, K. SHAW, J. FINN | Monday, September 13, 11:15 AM - 1:15 PM Poster Number F1-855 |
| Antibiotic Resistance in Staphylococcus aureus | Elevated Linezolid Resistance in Clinical Staphylococcus aureus cfr Isolates is Associated with Co-occurring Mutations in Ribosomal Protein L3 • J. B. LOCKE, G. MORALES, M. HILGERS, K. GC, S. RAHAWI, J. J. PICAZO, K. J. SHAW, J. L. STEIN | Tuesday, September 14, 11:15 AM - 1:15 PM Poster Number C1-1431 |
| Antibiotic Resistance in Staphylococcus aureus | Structure-Activity Relationships of Diverse Oxazolidinones for Linezolid-Resistant Staphylococcus aureus Strains Possessing Ribosomal Mutations or the cfr Methyltransferase Gene • J. B. LOCKE, J. FINN, M. HILGERS, S. RAHAWI, K. GC, G. MORALES, J. J. PICAZO, W. IM, K. J. SHAW, J. L. STEIN | Tuesday, September 14, 11:15 AM - 1:15 PM Poster Number C1-1431 |
| Antibiotic Resistance in Gram-Negative Bacteria Other than Enterobacteriacea | Evidence for Multiple Functionality of Campylobacter jejuni DNA Gyrase in Chromosomal Replication • D. C. BENSEN, A. H. WALTERS, M. CUNNINGHAM, L. W. TARI, K. J. SHAW, J. FINN | Tuesday, September 14, 11:15 AM - 1:15 PM Poster Number C1-1426 |
